Atypical parkinsonism and motor neuron syndrome in a Biosphere 2 participant: A possible complication of chronic hypoxia and carbon monoxide toxicity?
Identifieur interne : 003E05 ( Main/Exploration ); précédent : 003E04; suivant : 003E06Atypical parkinsonism and motor neuron syndrome in a Biosphere 2 participant: A possible complication of chronic hypoxia and carbon monoxide toxicity?
Auteurs : Brian K. Lassinger [États-Unis] ; Carolyn Kwak [États-Unis] ; Roy L. Walford [États-Unis] ; Joseph Jankovic [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2004-04.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Oxygène.
English descriptors
- KwdEn :
- Aged, Anoxia (chemically induced), Anoxia (physiopathology), Brain (drug effects), Brain (pathology), Brain (physiopathology), Carbon Monoxide (adverse effects), Carbon monoxide, Chronic Disease, Complication, Gait, Humans, Hypoxia, Magnetic Resonance Imaging, Male, Motor Neuron Disease (pathology), Motor Neuron Disease (physiopathology), Motor neuron, Neck, Nervous system diseases, Nitrous Oxide (adverse effects), Oxygen, Oxygen Consumption, Parkinsonian Disorders (diagnosis), Parkinsonian Disorders (physiopathology), Parkinsonism, Severity of Illness Index, Spinal Osteophytosis (pathology), Toxicity, biosphere, gait disorder, hypoxia, motor neuron disease, parkinsonism.
- MESH :
- chemical , adverse effects : Carbon Monoxide, Nitrous Oxide.
- chemically induced : Anoxia.
- diagnosis : Parkinsonian Disorders.
- drug effects : Brain.
- pathology : Brain, Motor Neuron Disease, Spinal Osteophytosis.
- physiopathology : Anoxia, Brain, Motor Neuron Disease, Parkinsonian Disorders.
- Aged, Chronic Disease, Gait, Humans, Magnetic Resonance Imaging, Male, Neck, Oxygen Consumption, Severity of Illness Index.
Abstract
Exogenous toxins and chronic hypoxia have been implicated in the etiopathogenesis of a variety of neurological disorders, but it is not always possible to establish a cause–effect relationships. We describe a patient who presented with an unusual gait disorder and progressive motor neuron disease after residing for 2 years within Biosphere 2, a scientifically engineered dome, tightly sealed to allow miniscule exchange of air between its atmosphere and the earth's atmosphere. We postulate that this unusual syndrome resulted from chronic hypoxia possibly coupled with carbon monoxide and nitrous oxide exposure. © 2004 Movement Disorder Society
Url:
DOI: 10.1002/mds.20076
Affiliations:
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Walford</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, University of California School of Medicine, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName><orgName type="university" n="3">Baylor College of Medicine</orgName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. 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We describe a patient who presented with an unusual gait disorder and progressive motor neuron disease after residing for 2 years within Biosphere 2, a scientifically engineered dome, tightly sealed to allow miniscule exchange of air between its atmosphere and the earth's atmosphere. We postulate that this unusual syndrome resulted from chronic hypoxia possibly coupled with carbon monoxide and nitrous oxide exposure. © 2004 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li><li>Texas</li></region><settlement><li>Houston</li></settlement><orgName><li>Baylor College of Medicine</li></orgName></list><tree><country name="États-Unis"><region name="Texas"><name sortKey="Lassinger, Brian K" sort="Lassinger, Brian K" uniqKey="Lassinger B" first="Brian K." last="Lassinger">Brian K. Lassinger</name></region><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name><name sortKey="Kwak, Carolyn" sort="Kwak, Carolyn" uniqKey="Kwak C" first="Carolyn" last="Kwak">Carolyn Kwak</name><name sortKey="Walford, Roy L" sort="Walford, Roy L" uniqKey="Walford R" first="Roy L." last="Walford">Roy L. Walford</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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